Back to Search
Start Over
[Combined treatment with resection, intraoperative hypotonic and post-operative systemic chemotherapy using cis-platinum for a mediastinal yolk sac tumor: a case report].
- Source :
-
Kyobu geka. The Japanese journal of thoracic surgery [Kyobu Geka] 1996 Dec; Vol. 49 (13), pp. 1110-3. - Publication Year :
- 1996
-
Abstract
- Generally yolk sac tumor in the mediastinum is a rare and highly malignant neoplasm. We report a case of yolk sac tumor, which was treated with resection, and then intraoperative hypotonic and postoperative systemic chemotherapy. A 33-year-old man was diagnosed as a mediastinal tumor with chest X-ray and chest CT findings. At operation he had mediastinal tumor which invaded to the part of the right upper lobe and pericardium, disseminated on the right diaphragm. A large tumor was removed with partial pericardiectomy and wedge resection of the right upper lobe. After resection hypotonic chemotherapy with cis-platinum was performed. This tumor had endodermal sinus structure, Schiller-Duval body, and eosinophilic hyaline globolus which were histological characteristics of yolk sac tumor, and the value of serum alpha-fetoprotein (AFP) was high. After operation with this diagnosis systemic chemotherapy consisted of cis-platinum, etoposide were performed. Patient was discharged uneventfully 8 months later.
- Subjects :
- Adult
Combined Modality Therapy
Drug Administration Schedule
Endodermal Sinus Tumor drug therapy
Endodermal Sinus Tumor surgery
Humans
Hypotonic Solutions administration & dosage
Male
Mediastinal Neoplasms drug therapy
Mediastinal Neoplasms surgery
Cisplatin administration & dosage
Endodermal Sinus Tumor therapy
Mediastinal Neoplasms therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0021-5252
- Volume :
- 49
- Issue :
- 13
- Database :
- MEDLINE
- Journal :
- Kyobu geka. The Japanese journal of thoracic surgery
- Publication Type :
- Academic Journal
- Accession number :
- 8958689