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Syntheses and pharmacological properties of new 2-aminobenzimidazole derivatives.
- Source :
-
Bollettino chimico farmaceutico [Boll Chim Farm] 1996 Jan; Vol. 135 (1), pp. 18-23. - Publication Year :
- 1996
-
Abstract
- The paper reports the structures, syntheses and pharmacological properties of new compounds having a 2-aminobenzimidazole group. They exhibit various activities: histamine H1- and H2-receptors blocking activities, antilipidemic and platelet antiaggregatory, anti-inflammatory and analgesic properties, antimicrobial, fungicidal, parasiticide, antiarrythmic activity and muscle relaxant, comparable to those of drugs used in therapy.
- Subjects :
- Anthelmintics chemical synthesis
Anthelmintics pharmacology
Anti-Arrhythmia Agents chemical synthesis
Anti-Arrhythmia Agents pharmacology
Anti-Infective Agents chemical synthesis
Anti-Infective Agents pharmacology
Anti-Inflammatory Agents, Non-Steroidal chemical synthesis
Anti-Inflammatory Agents, Non-Steroidal pharmacology
Benzimidazoles pharmacology
Histamine H1 Antagonists chemical synthesis
Histamine H1 Antagonists pharmacology
Histamine H2 Antagonists chemical synthesis
Histamine H2 Antagonists pharmacology
Hypolipidemic Agents chemical synthesis
Hypolipidemic Agents pharmacology
Muscle Relaxants, Central chemical synthesis
Muscle Relaxants, Central pharmacology
Benzimidazoles chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 0006-6648
- Volume :
- 135
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Bollettino chimico farmaceutico
- Publication Type :
- Academic Journal
- Accession number :
- 9004736