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[Low molecular weight heparins. Implications in anesthesia and resuscitation].
- Source :
-
Revista espanola de anestesiologia y reanimacion [Rev Esp Anestesiol Reanim] 1997 Feb; Vol. 44 (2), pp. 70-8. - Publication Year :
- 1997
-
Abstract
- Low molecular weight heparins are a group of drugs that have only recently been introduced in clinical practice. The are widely used for prophylaxis in thromboembolic disease and are being employed increasingly to treat established venous thrombosis. One way in which these drugs are often used is for prophylaxis in the perioperative period for patients at high risk of developing venous thromboembolism, and the anesthesiologist must therefore be familiar with the main aspects of this application. We review pharmacological characteristics of these drugs as well as the literature on low molecular weight heparins, stressing points of main interest to the anesthesiologist and intensive care recovery unit specialist, namely adverse effects (mainly bleeding) and the implications that use of low molecular weight heparin will have on choice of anesthetic (in particular the dilemma of whether to use local/regional anesthesia).
- Subjects :
- Anesthesia, Spinal adverse effects
Anticoagulants chemistry
Anticoagulants pharmacology
Factor Xa Inhibitors
Female
Fibrinolytic Agents chemistry
Fibrinolytic Agents pharmacology
Hemorrhage chemically induced
Hemorrhage prevention & control
Heparin, Low-Molecular-Weight antagonists & inhibitors
Heparin, Low-Molecular-Weight chemistry
Heparin, Low-Molecular-Weight pharmacology
Humans
Male
Postoperative Complications chemically induced
Pregnancy
Pregnancy Complications, Hematologic drug therapy
Protamines pharmacology
Protamines therapeutic use
Subarachnoid Hemorrhage etiology
Subarachnoid Hemorrhage prevention & control
Thrombin antagonists & inhibitors
Anticoagulants therapeutic use
Fibrinolytic Agents therapeutic use
Heparin, Low-Molecular-Weight therapeutic use
Postoperative Complications prevention & control
Thromboembolism prevention & control
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0034-9356
- Volume :
- 44
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Revista espanola de anestesiologia y reanimacion
- Publication Type :
- Academic Journal
- Accession number :
- 9148359