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Hypertension in the hemodialysis population: any relation to one-year survival?
- Source :
-
American journal of kidney diseases : the official journal of the National Kidney Foundation [Am J Kidney Dis] 1996 Nov; Vol. 28 (5), pp. 737-40. - Publication Year :
- 1996
-
Abstract
- Few studies have quantified the effect of hypertension on survival in the hemodialysis population. We report the effect of hypertension on 1-year survival in 649 hemodialysis patients (89% black). In univariate analysis, hypertension was associated with improved 1-year survival (relative risk [RR], 0.48; P = 0.002 compared with normotensive patients). This effect of hypertension was mostly caused by the associated antihypertensive treatment because untreated hypertensive patients had survival rates equal to normotensive patients (RR, 0.87; P = 0.70). On the other hand, treated hypertensive patients fared better than normotensive patients (RR, 0.41; P = 0.0006). This was also true in multivariate analysis, in which antihypertensive treatment was associated with reduced RR (RR, 0.55; P = 0.02) whereas the level of blood pressure per se was insignificant (RR, 0.99; P = 0.63 per 1 mm Hg increase in predialysis mean arterial pressure). Other factors of significance in multivariate analysis included age (RR, 1.03/y; P = 0.0004), serum albumin (RR, 0.38/g; P = 0.002), and diabetes mellitus (RR, 1.58; P = 0.06). Our study suggests that antihypertensive treatment has a favorable effect on survival in the hemodialysis population irrespective of the level of blood pressure control.
- Subjects :
- Antihypertensive Agents therapeutic use
Female
Follow-Up Studies
Humans
Hypertension drug therapy
Male
Middle Aged
Multivariate Analysis
Proportional Hazards Models
Risk Factors
Survival Analysis
Hypertension mortality
Kidney Failure, Chronic mortality
Kidney Failure, Chronic therapy
Renal Dialysis mortality
Subjects
Details
- Language :
- English
- ISSN :
- 0272-6386
- Volume :
- 28
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- American journal of kidney diseases : the official journal of the National Kidney Foundation
- Publication Type :
- Academic Journal
- Accession number :
- 9158213
- Full Text :
- https://doi.org/10.1016/s0272-6386(96)90257-7