Back to Search Start Over

[A comparative analysis of proteins from persistent and antigen-defective strains of tick-borne encephalitis virus].

Authors :
Pressman EK
Malenko GV
Pogodina VV
Matveeva VA
Bochkova NG
Levina LS
Source :
Voprosy virusologii [Vopr Virusol] 1997 Mar-Apr; Vol. 42 (2), pp. 53-6.
Publication Year :
1997

Abstract

Structural (E) and three nonstructural (NS1, NS3, and NS5) proteins of persistent and antigen-defective strains of tick-borne encephalitis virus are compared by immunoblotting with monoclonal antibodies to the corresponding proteins of strain Sofyin. Appreciable phenotypical differences were revealed between antigen-defective strains, but no immunological modifications as concerns the studied antigenic structures. The size of the reference NS3 protein differed from that of the persistent virus strains. Similar proteins detected in the antigenic preparations of strain Zausaev may have notable modifications.

Details

Language :
Russian
ISSN :
0507-4088
Volume :
42
Issue :
2
Database :
MEDLINE
Journal :
Voprosy virusologii
Publication Type :
Academic Journal
Accession number :
9182398