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Obsessive compulsive symptoms in Gilles de la Tourette syndrome and obsessive compulsive disorder: differences by diagnosis and family history.
- Source :
-
American journal of medical genetics [Am J Med Genet] 1997 Jul 25; Vol. 74 (4), pp. 432-8. - Publication Year :
- 1997
-
Abstract
- The distribution of obsessive compulsive symptoms was compared in 16 individuals with primary obsessive compulsive disorder (OCD) and 16 individuals with Gilles de la Tourette syndrome (GTS) and associated obsessive compulsive behaviors (OCB). The two groups showed significant differences in the distribution of OC symptomatology. Furthermore, those OCD probands who shared a similar symptom profile with GTS individuals all had a positive family history of OCD. All of the other OCD probands were isolated cases. Implications of this finding on the etiology and pathogenesis of the two disorders are discussed.
- Subjects :
- Adolescent
Adult
Basal Ganglia physiopathology
Child
Dopamine physiology
Female
Frontal Lobe physiopathology
Gyrus Cinguli physiopathology
Humans
Male
Middle Aged
Obsessive-Compulsive Disorder etiology
Obsessive-Compulsive Disorder genetics
Obsessive-Compulsive Disorder physiopathology
Psychological Tests
Serotonin physiology
Thalamus physiopathology
Tourette Syndrome etiology
Tourette Syndrome genetics
Tourette Syndrome physiopathology
Compulsive Behavior
Obsessive Behavior
Obsessive-Compulsive Disorder psychology
Tourette Syndrome psychology
Subjects
Details
- Language :
- English
- ISSN :
- 0148-7299
- Volume :
- 74
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- American journal of medical genetics
- Publication Type :
- Academic Journal
- Accession number :
- 9259380
- Full Text :
- https://doi.org/10.1002/(sici)1096-8628(19970725)74:4<432::aid-ajmg15>3.0.co;2-j