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Colloidal silicic acid for the treatment of psoriatic skin lesions, arthropathy and onychopathy. A pilot study.
- Source :
-
The Journal of international medical research [J Int Med Res] 1997 Jul-Aug; Vol. 25 (4), pp. 206-9. - Publication Year :
- 1997
-
Abstract
- In a randomized, double-blind study, patients with chronic plaque-type psoriasis were either treated with 30 ml colloidal silicic acid gel, orally, daily, and topically with the same gel (n = 15), or were treated identically with placebo gel (n = 15) for 3 months. One stable psoriatic lesion on the knee or elbow was treated topically and followed throughout the study. Five patients in the treated group and seven controls had psoriatic arthropathy and 11 treated patients and 12 controls had psoriatic onychopathy. Three treated patients and six controls withdrew because of skin irritation or lack of efficacy. In the treated group there were clear improvements in scaling, induration and erythema after treatment. The nail changes were cured in five of 10 evaluable patients in the treated group and joint pain was reduced by almost half in the four evaluable patients with arthropathy. There were no such improvements in the placebo group.
- Subjects :
- Administration, Oral
Administration, Topical
Arthritis, Psoriatic pathology
Arthritis, Psoriatic physiopathology
Colloids
Double-Blind Method
Female
Humans
Male
Middle Aged
Nail Diseases pathology
Nail Diseases physiopathology
Pain drug therapy
Pilot Projects
Psoriasis pathology
Psoriasis physiopathology
Silicic Acid adverse effects
Arthritis, Psoriatic drug therapy
Nail Diseases drug therapy
Psoriasis drug therapy
Silicic Acid administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 0300-0605
- Volume :
- 25
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- The Journal of international medical research
- Publication Type :
- Academic Journal
- Accession number :
- 9283994
- Full Text :
- https://doi.org/10.1177/030006059702500406