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Treatment of recurrent conjunctival epithelial neoplasia with topical mitomycin C.
- Source :
-
American journal of ophthalmology [Am J Ophthalmol] 1997 Sep; Vol. 124 (3), pp. 397-9. - Publication Year :
- 1997
-
Abstract
- Purpose: To study the effect of topical mitomycin C on conjunctival squamous neoplasia.<br />Methods: Three patients with recurrent conjunctival epithelial neoplasia were treated with topical mitomycin C 0.04%.<br />Results: Six to 9 months after treatment, no patient had clinical evidence of tumor recurrence. Conjunctival biopsy in two patients and cytology in one patient showed no evidence of tumor 1 to 4 months after treatment. One patient required short-term treatment for corneal edema and epithelial toxicity.<br />Conclusion: Topical mitomycin C caused tumor regression without recurrence for 6 to 9 months after treatment.
- Subjects :
- Administration, Topical
Aged
Aged, 80 and over
Antibiotics, Antineoplastic administration & dosage
Carcinoma in Situ pathology
Conjunctival Neoplasms pathology
Female
Humans
Male
Middle Aged
Mitomycin administration & dosage
Ophthalmic Solutions
Recurrence
Remission Induction
Antibiotics, Antineoplastic therapeutic use
Carcinoma in Situ drug therapy
Conjunctival Neoplasms drug therapy
Mitomycin therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9394
- Volume :
- 124
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- American journal of ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 9439368
- Full Text :
- https://doi.org/10.1016/s0002-9394(14)70834-7