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Effect of dexamethasone and corticosterone on activity levels of ATPase, phosphomonoesterases and phosphodiesterase in liver, muscle and testis of post-hatched White Leghorn chicks.
- Source :
-
Indian journal of experimental biology [Indian J Exp Biol] 1997 Sep; Vol. 35 (9), pp. 977-82. - Publication Year :
- 1997
-
Abstract
- Muscle ATPase activity did not show much change with any of the treatments, while hepatic total and Ca(2+)-Mg(2+)-ATPase activities were decreased with low dose of dexamethasone (DXM(L) and enzyme activity in general was increased with both high dose of DXM(H) and corticosterone. Total and Ca(2+)-Mg(2+)-ATPases were increased in testis of corticosterone treated chicks. Acid phosphatase activity of testis was increased with DXM(H) and decreased with DXM(L) while the enzyme activity in all the three tissues was increased with corticosterone. Muscle alkaline phosphatase activity was decreased with DXM treatments while that of testis was decreased with both DXM(H) and corticosterone treatments. Hepatic PDE activity was decreased with DXM and increased with corticosterone while muscle PDE activity was decreased under both DXM(H) and corticosterone treatments. The results suggest that both hypo. and hypercorticalism can induce tissue specific differential alterations in phosphomonoesterases, ATPases and PDE during early phases of post-natal development of chicks.
- Subjects :
- Adenosine Triphosphatases metabolism
Animals
Chickens
Liver enzymology
Male
Muscle, Skeletal enzymology
Phosphoric Diester Hydrolases metabolism
Phosphoric Monoester Hydrolases metabolism
Testis enzymology
Corticosterone pharmacology
Dexamethasone pharmacology
Glucocorticoids pharmacology
Liver drug effects
Muscle, Skeletal drug effects
Testis drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0019-5189
- Volume :
- 35
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Indian journal of experimental biology
- Publication Type :
- Academic Journal
- Accession number :
- 9475079