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[The effect of activated macrophage products on neurite growth in an organotypic culture of chick embryo sensory ganglia].
- Source :
-
Tsitologiia [Tsitologiia] 1997; Vol. 39 (8), pp. 694-8. - Publication Year :
- 1997
-
Abstract
- Murine peritoneal macrophages, activated by BCG vaccine, and human peripheral blood monocytes, activated by lipopolysaccharides, exerted neurite stimulating or neurite inhibiting effects in various periods of activation. The supernatants of these preparations were active in organotypic culture of chick embryo dorsal root ganglia. The inhibition of neurite growth on the 1st day of cultivation was followed by the neurite-stimulating effect. The fluctuation of neurite-inhibition and neurite-stimulation effect of macrophage supernatants suggest the availability of certain changes in cytokine composition in different periods of macrophage activation.
- Subjects :
- Animals
Axons ultrastructure
BCG Vaccine pharmacology
Cell Division drug effects
Chick Embryo
Culture Techniques
Ganglia, Sensory ultrastructure
Humans
Lipopolysaccharides pharmacology
Macrophage Activation drug effects
Macrophages, Peritoneal drug effects
Macrophages, Peritoneal immunology
Mice
Mice, Inbred C57BL
Monocytes drug effects
Monocytes immunology
Time Factors
Axons drug effects
Ganglia, Sensory drug effects
Macrophage-Activating Factors pharmacology
Subjects
Details
- Language :
- Russian
- ISSN :
- 0041-3771
- Volume :
- 39
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Tsitologiia
- Publication Type :
- Academic Journal
- Accession number :
- 9490507