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Software for constructing and verifying pedigrees within large genealogies and an application to the Old Order Amish of Lancaster County.

Authors :
Agarwala R
Biesecker LG
Hopkins KA
Francomano CA
Schaffer AA
Source :
Genome research [Genome Res] 1998 Mar; Vol. 8 (3), pp. 211-21.
Publication Year :
1998

Abstract

This paper describes PedHunter, a software package that facilitates creation and verification of pedigrees within large genealogies. A frequent problem in medical genetics is to connect distant relatives with a pedigree. PedHunter uses methods from graph theory to solve two versions of the pedigree connection problem for genealogies as well as other pedigree analysis problems. The pedigrees are produced by PedHunter as files in LINKAGE format ready for linkage analysis. PedHunter uses a relational database of genealogy data, with tables in specified format, for all calculations. The functionality and utility of PedHunter are illustrated by examples using the Amish Genealogy Database (AGDB), which was created for the Old Order Amish community of Lancaster County, Pennsylvania.

Details

Language :
English
ISSN :
1088-9051
Volume :
8
Issue :
3
Database :
MEDLINE
Journal :
Genome research
Publication Type :
Academic Journal
Accession number :
9521925
Full Text :
https://doi.org/10.1101/gr.8.3.211