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The management of cryptococcal meningitis in Papua New Guinea.
- Source :
-
Papua and New Guinea medical journal [P N G Med J] 1996 Mar; Vol. 39 (1), pp. 67-73. - Publication Year :
- 1996
-
Abstract
- Cryptococcal meningitis is a difficult disease to treat and requires biochemical and haematological monitoring to detect the common adverse effects of treatment. Combination therapy with amphotericin B and flucytosine for at least 6 weeks is the best treatment so far evaluated. The role of azole drugs should become clearer as the results of large multicentre studies become available in the future. High case fatality and morbidity rates despite standard treatment suggest that other ancillary treatments such as corticosteroids and other treatments directed at lowering raised intracranial pressure may also be required in some patients.
- Subjects :
- Amphotericin B administration & dosage
Amphotericin B adverse effects
Amphotericin B therapeutic use
Anti-Inflammatory Agents therapeutic use
Antifungal Agents administration & dosage
Antifungal Agents adverse effects
Antifungal Agents therapeutic use
Cause of Death
Drug Combinations
Drug Monitoring
Fluconazole therapeutic use
Flucytosine administration & dosage
Flucytosine adverse effects
Flucytosine therapeutic use
Humans
Hydrocortisone therapeutic use
Immunocompetence
Intracranial Hypertension drug therapy
Intracranial Pressure drug effects
Itraconazole therapeutic use
Meningitis, Cryptococcal blood
Multicenter Studies as Topic
Papua New Guinea
Meningitis, Cryptococcal drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0031-1480
- Volume :
- 39
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Papua and New Guinea medical journal
- Publication Type :
- Academic Journal
- Accession number :
- 9522853