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The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26.

Authors :
Koehler MR
Wissinger B
Gorboulev V
Koepsell H
Schmid M
Source :
Cytogenetics and cell genetics [Cytogenet Cell Genet] 1997; Vol. 79 (3-4), pp. 198-200.
Publication Year :
1997

Abstract

Polyspecific transporters for organic cations (OCT) belong to a new protein family which also include organic anion transporters. The first human transporters from this family (OCT1, OCT2) have been recently cloned. They translocate small cations like tetraethylammonium, choline and monoamine neurotransmitters and are involved in hepatic and renal cation excretion, respectively. We have localized the OCT1 and OCT2 genes (SLC22A1, SLC22A2) on chromosome 6q26.

Details

Language :
English
ISSN :
0301-0171
Volume :
79
Issue :
3-4
Database :
MEDLINE
Journal :
Cytogenetics and cell genetics
Publication Type :
Academic Journal
Accession number :
9605850
Full Text :
https://doi.org/10.1159/000134720