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Thyroid volume is progressively reduced as a sequela of neck irradiation for childhood Hodgkin's disease.
- Source :
-
Haematologica [Haematologica] 1998 Aug; Vol. 83 (8), pp. 754-6. - Publication Year :
- 1998
-
Abstract
- Thyroid volume reduction was observed, among 25 subjects off-therapy after Hodgkin's disease. The volume reduction was related to dose (p = 0.014) and time from radiotherapy (p = 0.01). The correlation was very specific since all patients with reduced volume had hypothyroidism, but not very sensitive since 25% of subjects with thyroid dysfunction had normal gland volume.
- Subjects :
- Adolescent
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Atrophy
Child
Child, Preschool
Combined Modality Therapy
Female
Hodgkin Disease drug therapy
Humans
Hypothyroidism etiology
Infant
Male
Neck radiation effects
Thyroid Function Tests
Thyroid Gland radiation effects
Hodgkin Disease radiotherapy
Radiation Injuries pathology
Radiotherapy adverse effects
Thyroid Gland pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0390-6078
- Volume :
- 83
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Haematologica
- Publication Type :
- Editorial & Opinion
- Accession number :
- 9793265