Back to Search Start Over

Detection of an antibothropic fraction in opossum (Didelphis marsupialis) milk that neutralizes Bothrops jararaca venom.

Authors :
Jurgilas PB
Neves-Ferreira AG
Domont GB
Moussatché H
Perales J
Source :
Toxicon : official journal of the International Society on Toxinology [Toxicon] 1999 Jan; Vol. 37 (1), pp. 167-72.
Publication Year :
1999

Abstract

An antibothropic fraction (ABF) from Didelphis marsupialis (opossum) serum, which is responsible for the neutralization of Bothrops jararaca venom was isolated by Perales et al. [Perales, J., Moussatché, H., Marangoni, S., Oliveira, B. and Domont, G. B. (1994). Isolation and partial characterization of an antibothropic complex from the serum of South American Didelphidae. Toxicon 32, 1237-1249]. The aim of this work was to verify the presence of this factor in opossum's milk, which could represent an additional protection for the neonatal opossum against bothropic venoms. An active milk fraction was isolated and showed similar physicochemical, structural, antigenic and biological properties when compared to ABF, indicating that they are probably the same protein.

Details

Language :
English
ISSN :
0041-0101
Volume :
37
Issue :
1
Database :
MEDLINE
Journal :
Toxicon : official journal of the International Society on Toxinology
Publication Type :
Academic Journal
Accession number :
9920488
Full Text :
https://doi.org/10.1016/s0041-0101(98)00175-5