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Intracranial Rosai-Dorfman disease mimicking multiple meningiomas in a child: a case report and review of the literature.
- Source :
- Child's Nervous System; Feb2015, Vol. 31 Issue 2, p317-323, 7p
- Publication Year :
- 2015
-
Abstract
- Objective: Rosai-Dorfman disease (RDD) is a rare idiopathic, non-neoplastic histioproliferative disease. Central nervous system (CNS) manifestations are extremely rare. In this paper, we describe a 6-year-old boy with intracranial RDD mimicking multiple meningiomas both clinically and radiologically. We reviewed the literature to understand the clinical behaviour, clinicopathological features and treatment options. Methods: A PubMed (US National Library of Medicine) search using the keywords 'Rosai-Dorfman disease' and 'central nervous system' was performed and citations were reviewed. Results: Eighty-five cases of RDD involving the CNS have been reported until date, and only 7 cases involved children. Of the 85 cases, 16 cases mimicked multiple meningiomas. Our case is the first to involve multiple lesions in a child under 14 years old. Conclusion: After reviewing the literature, we concluded that RDD should be considered as a differential diagnosis for lesions mimicking multiple meningiomas, especially in children. Resection of the intracranial lesion is the most effective treatment, and a definitive diagnosis should be based on histopathologic and immunocytochemical examinations. [ABSTRACT FROM AUTHOR]
- Subjects :
- CENTRAL nervous system cancer
SPINAL cord abnormalities
Subjects
Details
- Language :
- English
- ISSN :
- 02567040
- Volume :
- 31
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Child's Nervous System
- Publication Type :
- Academic Journal
- Accession number :
- 100632295
- Full Text :
- https://doi.org/10.1007/s00381-014-2536-y