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An enzyme logic bioprotonic transducer.
- Source :
- APL Materials; 2015, Vol. 3 Issue 1, p014906-1-014906-6, 6p
- Publication Year :
- 2015
-
Abstract
- Translating ionic currents into measureable electronic signals is essential for the integration of bioelectronic devices with biological systems.We demonstrate the use of a Pd/PdH<subscript>x</subscript> electrode as a bioprotonic transducer that connects H<superscript>+</superscript> currents in solution into an electronic signal. This transducer exploits the reversible formation of PdH<subscript>x</subscript> in solution according to PdH ← Pd + H<superscript>+</superscript> + e<superscript>-</superscript>, and the dependence of this formation on solution pH and applied potential. We integrate the protonic transducer with glucose dehydrogenase as an enzymatic AND gate for glucose and NAD<superscript>+</superscript>. PdH<subscript>x</subscript> formation and associated electronic current monitors the output drop in pH, thus transducing a biological function into a measurable electronic output. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 2166532X
- Volume :
- 3
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- APL Materials
- Publication Type :
- Academic Journal
- Accession number :
- 100777994
- Full Text :
- https://doi.org/10.1063/1.4900886