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Nickel-NHC-Catalyzed Cross-Coupling of 2-Methylsulfanylbenzofurans with Alkyl Grignard Reagents.
- Source :
- Synlett; 2015, Vol. 26 Issue 3, p327-330, 4p
- Publication Year :
- 2015
-
Abstract
- NiCl<subscript>2</subscript>(PPh<subscript>3</subscript>)(IPr) catalyzes cross-coupling reactions of 2-methylsulfanylbenzofurans with alkyl Grignard reagents. Other nickel complexes such as NiCl<subscript>2</subscript>(dppe) failed to catalyze the same reaction. The alkylation is applicable to the synthesis of a couple of protein tyrosine phosphatase inhibitors, 3-(4-biphenylyl)-2-alkylbenzofurans. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09365214
- Volume :
- 26
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Synlett
- Publication Type :
- Academic Journal
- Accession number :
- 100791880
- Full Text :
- https://doi.org/10.1055/s-0034-1378914