Copper-catalyzed C–N bond formation through C–H/N–H activation: a novel approach to the synthesis of multisubstituted ureas.

A copper-catalyzed cross-dehydrogenative coupling reaction that involves C–H activation of formamides and N–H activation of N-alkoxy amides has been developed. This protocol affords a novel approach to the synthesis of multisubstituted ureas under mild conditions. [ABSTRACT FROM AUTHOR]