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An efficient synthesis of optically active trifluoromethyl aldimines via asymmetric biomimetic transamination.

Authors :
Liu, Mao
Li, Jing
Xiao, Xiao
Xie, Ying
Shi, Yian
Source :
Chemical Communications; 2013, Vol. 49 Issue 14, p1404-1406, 3p
Publication Year :
2013

Abstract

This communication describes a chiral base-catalyzed asymmetric [1,3]-proton shift of trifluoromethyl ketimines, giving a wide variety of trifluoromethyl aldimines containing various functional groups with up to 94% ee. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
49
Issue :
14
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
100864113
Full Text :
https://doi.org/10.1039/c2cc37423d