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Nanoparticle-based immunoassays in the biomedical field.
- Source :
- Analyst; 2013, Vol. 138 Issue 4, p981-990, 10p
- Publication Year :
- 2013
-
Abstract
- Recent research has looked to develop innovative, powerful and novel biofunctionalized nanoparticles, controlling and tailoring their properties in a very predictable manner to meet the needs of clinic immunoassays in the biomedical field. This minireview briefly summarizes recent advances covering the last 3 years, exploiting nanoparticle-based electrochemical, optical, mass-sensitive, colorimetric and immunodipstick assays. The enormous signal enhancement associated with the use of nanoparticles and formation of nanoparticle–antibody–antigen assemblies provide the basis for sensitive detection of disease-related proteins or biomarkers. Rather than being exhaustive, this minireview focuses on selected examples to illustrate novel concepts and promising applications. Finally, a small amount of speculation of possible future developments in nanoparticle-based immunoassays is provided. [ABSTRACT FROM AUTHOR]
- Subjects :
- NANOPARTICLES
IMMUNOASSAY
BIOMARKERS
ANTIGENS
PROTEINS
IMMUNOGLOBULINS
Subjects
Details
- Language :
- English
- ISSN :
- 00032654
- Volume :
- 138
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Analyst
- Publication Type :
- Academic Journal
- Accession number :
- 100865944
- Full Text :
- https://doi.org/10.1039/c2an36500f