Back to Search
Start Over
Copper-catalyzed radical cascade cyclization for the synthesis of phosphorated indolines.
- Source :
- Chemical Communications; 2015, Vol. 51 Issue 19, p4101-4104, 4p
- Publication Year :
- 2015
-
Abstract
- A novel and convenient approach to the synthesis of various phosphorated indolines via a copper-catalyzed radical cascade cyclization reaction has been developed. The reaction employs cheap copper as the catalyst and K<subscript>2</subscript>S<subscript>2</subscript>O<subscript>8</subscript> as the oxidant under mild conditions. Various alkenes and P-radical precursors are compatible with this transformation. Preliminary mechanistic studies reveal that the addition of the P-radical may initiate the reaction, and then oxidative cyclization may be achieved to afford the desired product. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 51
- Issue :
- 19
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 101107507
- Full Text :
- https://doi.org/10.1039/c4cc10267c