Back to Search
Start Over
Analysis of Polar Precursors of 1,3,5,7-Tetranitro-1,3,5,7-tetrazocine (HMX) Using Hydrophilic Interaction Chromatography.
- Source :
- Propellants, Explosives, Pyrotechnics; Feb2015, Vol. 40 Issue 1, p133-137, 5p
- Publication Year :
- 2015
-
Abstract
- Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) is currently one of the most widely used explosives. 1,3,5,7-Tetraacetyl-1,3,5,7-tetraazacyclooctane (TAT) is an attractive precursor for the synthesis of HMX; the nitration of this key precursor results in both high yield and purity under mild condition. TAT can be prepared either by acetylation of 2,6-diacetyl-pentamethylenetetramine (DAPT) or by the condensation of ACN and 1,3,5-trioxane. However, TAT and DAPT are polar compounds, and are difficult to analyze using reverse phase liquid chromatography. Herein, a chromatography method for the direct separation of these polar compounds was developed using hydrophilic interaction chromatography (HILIC) using a Venusil HILIC column, with ACN/water (95/5, v/v) as the mobile phase. The chromatographic analysis and identification of these polar compounds provide valuable information for the optimization of the synthetic process of TAT. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 07213115
- Volume :
- 40
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Propellants, Explosives, Pyrotechnics
- Publication Type :
- Academic Journal
- Accession number :
- 101300745
- Full Text :
- https://doi.org/10.1002/prep.201400070