Back to Search Start Over

Haematological malignancies: at the forefront of immunotherapeutic innovation.

Authors :
Bachireddy, Pavan
Burkhardt, Ute E.
Rajasagi, Mohini
Wu, Catherine J.
Source :
Nature Reviews Cancer; Apr2015, Vol. 15 Issue 4, p201-215, 15p
Publication Year :
2015

Abstract

The recent successes of cancer immunotherapies have stimulated interest in the potential widespread application of these approaches; haematological malignancies have provided both initial proofs of concept and an informative testing ground for various immune-based therapeutics. The immune-cell origin of many of the blood malignancies provides a unique opportunity both to understand the mechanisms of cancer immune responsiveness and immune evasion, and to exploit these mechanisms for therapeutic purposes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1474175X
Volume :
15
Issue :
4
Database :
Complementary Index
Journal :
Nature Reviews Cancer
Publication Type :
Academic Journal
Accession number :
101720501
Full Text :
https://doi.org/10.1038/nrc3907