Relationship between maximal fat oxidation and oxygen uptake: comparison between type 2 diabetes patients and healthy sedentary subjects.

The contribution of fat oxidation to energy production during exer- cise is influenced by intensity of exercise. The aim of this study was to assess the relationship between the highest value of fat oxidation rate (FAT_max) and the oxygen uptake (VO₂) in sedentary type 2 diabetes (T2D) patients vs healthy sedentary subjects. Sedentary T2D patients and healthy sedentary subjects were evaluated to a graded exercise test, and oxygen uptake and fat oxidation rate were detected. Data show that in T2D patients fat oxidation rate is not impaired and the positive linear correlation between FAT_max and both VO₂ and VO_2max suggests that even in T2D patients the muscle oxidative capacity might increase in response to aerobic training. [ABSTRACT FROM AUTHOR]