Back to Search
Start Over
Success and failure of the cellular immune response against HIV-1.
- Source :
- Nature Immunology; Jun2015, Vol. 16 Issue 6, p563-570, 8p
- Publication Year :
- 2015
-
Abstract
- The cellular immune response to HIV-1 has now been studied in extraordinary detail. A very large body of data provides the most likely reasons that the HIV-specific cellular immune response succeeds in a small number of people but fails in most. Understanding the success and failure of the HIV-specific cellular immune response has implications that extend not only to immunotherapies and vaccines for HIV-1 but also to the cellular immune response in other disease states. This Review focuses on the mechanisms that are most likely responsible for durable and potent immunologic control of HIV-1. Although we now have a detailed picture of the cellular immune responses to HIV-1, important questions remain regarding the nature of these responses and how they arise. [ABSTRACT FROM AUTHOR]
- Subjects :
- CELLULAR immunity
IMMUNE response
HIV infections
IMMUNOLOGY
IMMUNOTHERAPY
Subjects
Details
- Language :
- English
- ISSN :
- 15292908
- Volume :
- 16
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Nature Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 102779188
- Full Text :
- https://doi.org/10.1038/ni.3161