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Long-term efficacy of biofeedback therapy in patients with dyssynergic defecation: results of a median 44 months follow-up.
- Source :
- Neurogastroenterology & Motility; Jun2015, Vol. 27 Issue 6, p787-795, 9p
- Publication Year :
- 2015
-
Abstract
- Background The beneficial effect of biofeedback therapy ( BFT) over a period of more than 2 years has not been studied in a large group of patients. The aim of this study was to evaluate the long-term efficacy of BFT for dyssynergic defecation ( DD). Methods We evaluated the results for 347 consecutive constipated patients with DD who underwent BFT for a median of five sessions between 2004 and 2009. Initial responses were assessed immediately after the completion of BFT. A responder was defined as a subject with at least a three-point improvement from before to after BFT on an 11-point global bowel satisfaction ( GBS) scale, or a two-point improvement if the baseline GBS was more than six points. The probability of remaining a responder was estimated by non-parametric maximum likelihood estimation. Key Results The initial response rate to BFT was 72.3% ( n = 251), Parkinson's disease and higher baseline GBS scores were associated with initial non-response. The long-term efficacy of BFT was analyzed in 103 patients who were followed up for more than 6 months; the initial effects of BFT were maintained in 85 of the patients (82.5%) during a median of 44 months of follow-up ( IQR = 12-68). The probability of remaining a responder was 60% at 2 years, and 58% at 5 years. Conclusions & Inferences The efficacy of BFT is maintained for more than 2 years after BFT in a considerable proportion of constipated patients with DD. BFT is effective and durable treatment for managing DD. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13501925
- Volume :
- 27
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Neurogastroenterology & Motility
- Publication Type :
- Academic Journal
- Accession number :
- 102855558
- Full Text :
- https://doi.org/10.1111/nmo.12552