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Natural history of prenatal isolated muscular ventricular septal defects.
- Source :
- Journal of the Turkish-German Gynecological Association; Jun2014, Vol. 15 Issue 2, p96-99, 4p, 1 Diagram, 2 Charts
- Publication Year :
- 2014
-
Abstract
- Objective: To evaluate the natural history of isolated muscular ventricular septal (m-VSD) defects during gestation and up to 1 year postnatally, as well as the association with chromosomal anomalies. Material and Methods: Between August 2007 and July 2012, 76 fetuses with isolated m-VSDs represented the study population. The following variables were evaluated: site and size of the m-VSDs, presence of chromosomal anomalies, pregnancy outcome, and spontaneous closure rate from diagnosis up to 1 year postnatally. Results: Of the 76 cases with m-VSD, 1 fetus died after birth and 31 cases were lost to follow-up after birth. Thus, a total of 44 fetuses reached their first year of postnatal life, and these cases were available for analysis. Three (6.8%) of 44 defects closed spontaneously in utero, 33 (75%) closed within 1 year, and 8 (18.2%) remained patent. Overall, spontaneous closure occurred more frequently in the apical defects, but no significant difference was found for spontaneous closure between the mid-muscular and apical defects (p > 0.05). Also, 83.8% (36 of 44) of defects ≤3 mm closed during gestation or the first year of life. Conclusion: We infer that m-VSDs have a high spontaneous closure rate during the first year of life. Also, small m-VSDs frequently close spontaneously. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13090399
- Volume :
- 15
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Journal of the Turkish-German Gynecological Association
- Publication Type :
- Academic Journal
- Accession number :
- 103113752
- Full Text :
- https://doi.org/10.5152/jtgga.2014.0012