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A study of topical methyl-aminolaevulinate red-light photodynamic therapy in the treatment of actinic keratosis in Chinese patients: a Singaporean experience.
- Source :
- Clinical & Experimental Dermatology; Jul2015, Vol. 40 Issue 5, p502-506, 5p, 1 Color Photograph, 1 Chart
- Publication Year :
- 2015
-
Abstract
- Background The incidence of skin cancers has been increasing in Singapore, owing to the country's location near the equator and its ageing population. Topical photodynamic therapy ( PDT) is a treatment method employing light and a topical photosensitizer to treat actinic keratosis ( AK). Most published data to date on PDT have been drawn from studies of patient with Fitzpatrick skin phototypes I and II. Aim To evaluate the effectiveness of PDT in the treatment of AK in patients with skin phototype IV in Singapore. Methods This was a retrospective analysis of 13 East Asian patients with AK treated with PDT at the National Skin Centre, Singapore, from 2006 to 2013. Results The overall clearance rate of AK at 3 months was 81.8% (9 of 11 patients; the other 2 were lost to follow-up). Mild to moderate pain during therapy was a common adverse event. Conclusions PDT is a useful treatment method for AK in East Asian patients with skin phototype IV. Further larger prospective studies will be needed to evaluate its overall efficacy in East Asian patients. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03076938
- Volume :
- 40
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Clinical & Experimental Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 103340989
- Full Text :
- https://doi.org/10.1111/ced.12637