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Toward the Supramolecular Cyclodextrin Dimers Using Nucleobase Pairs.

Authors :
Legros, Vanessa
Hamon, Florian
Violeau, Bruno
Turpin, Frédéric
Djedaini-Pilard, Florence
Désiré, Jérôme
Len, Christophe
Source :
Synthesis; 2011, Vol. 2011 Issue 2, p235-242, 8p
Publication Year :
2011

Abstract

The synthesis of eleven new cyclodextrin derivatives having nucleobase moiety - thymin-1-yl, adenin-9-yl, and guanin- 9-yl - is described. These two moieties are linked by different spacers, such as aminoethyl and 1,2,3-triazolyl group. Direct nucleophilic substitution and 1,3-dipolar cycloaddition were performed in good yields (13-73%) for some of the synthesized compounds. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397881
Volume :
2011
Issue :
2
Database :
Complementary Index
Journal :
Synthesis
Publication Type :
Academic Journal
Accession number :
103536230
Full Text :
https://doi.org/10.1055/s-0030-1258354