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Design, Synthesis, and Biological Evaluations of Several Y-26732 Analogues.
- Source :
- Journal of Heterocyclic Chemistry; Jul2015, Vol. 52 Issue 4, p1212-1218, 7p
- Publication Year :
- 2015
-
Abstract
- A series of pyridine Rho kinase inhibitors were designed and synthesized utilizing the ligand-binding pocket model with Y-26732 as the lead compound. These compounds were evaluated on cell lines for their biological activities. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0022152X
- Volume :
- 52
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Journal of Heterocyclic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 108612517
- Full Text :
- https://doi.org/10.1002/jhet.2238