Fulminant hepatic failure after intravenous injection of sublingual buprenorphine in a patient with hepatitis C.

Key Clinical Message A 20-year-old indigenous Australian male was admitted to the intensive care unit with fulminant hepatic failure secondary to intravenous use of buprenorphine, which had been prescribed sublingually for opioid dependence. Intravenous buprenorphine-induced hepatitis is well recognized, however, life-threatening fulminant hepatic failure has not previously been reported. [ABSTRACT FROM AUTHOR]