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BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function.
- Source :
- eLife; Aug2015, p1-23, 23p
- Publication Year :
- 2015
-
Abstract
- The article discusses a study which reveals the ability of BAG2, a protein of Bcl-2 associated athanogene (BAG) family to promote the accumulation of mutant p53 (mutp53) proteins and gain-of-function (GOF) in tumors.
- Subjects :
- BCL-2 genes
P53 protein
NEOPLASTIC cell transformation
Subjects
Details
- Language :
- English
- ISSN :
- 2050084X
- Database :
- Complementary Index
- Journal :
- eLife
- Publication Type :
- Academic Journal
- Accession number :
- 109355136
- Full Text :
- https://doi.org/10.7554/eLife.08401