T1 mapping - beware regional variations.

The article focuses on T1 mapping in ischaemic heart disease. It states that important part of image post-processing to measure myocardial T1 values is selection of region of interest (ROI) and it can be drawn on each raw image obtained from the T1 sequence or on the pixel-by-pixel map. It mentions that ROIs are related to a number of factors including magnetic susceptibility artefacts, issues pertaining to receiver coil sensitivity and signal gradient between septal and lateral myocardium.