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Molekularbiologische Methoden zur HLA-Typisierung.
- Source :
- BioSpektrum; Nov2015, Vol. 21 Issue 7, p721-723, 3p
- Publication Year :
- 2015
-
Abstract
- The success of allogeneic stem cell transplantation depends upon the degree of human leukocyte antigen (HLA) compatibility between the donor and patient since T-cell responses to foreign HLA molecules can result in aggressive immune responses. The human HLA locus on chromosome 6 is highly polymorphic within the population. Due to the large number of allels, the exact determination of the individual HLA polymorphisms (HLA typing) is a technically challenging task requiring different molecular biological procedures. [ABSTRACT FROM AUTHOR]
Details
- Language :
- German
- ISSN :
- 09470867
- Volume :
- 21
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- BioSpektrum
- Publication Type :
- Academic Journal
- Accession number :
- 110861106
- Full Text :
- https://doi.org/10.1007/s12268-015-0639-y