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A new diketopiperazine derivative from a deep sea-derived Streptomyces sp. SCSIO 04496.
- Source :
- Natural Product Research; Jan2016, Vol. 30 Issue 2, p138-143, 6p
- Publication Year :
- 2016
-
Abstract
- A new diketopiperazine (DKP) derivative, (6R,3Z)-3-benzylidene-6-isobutyl-1-methyl piperazine-2,5-dione (1), as well as five known DKPs 2–6 was isolated from a deep sea-derived Streptomyces sp. SCSIO 04496. The structure of 1 was elucidated using a combination of 1D and 2D NMR, HR-ESI-MS and chiral-phase HPLC techniques. Compounds 1–6 did not show cytotoxic activity at a concentration of 100 μM in bioactivity assay. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 30
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 111556298
- Full Text :
- https://doi.org/10.1080/14786419.2015.1045509