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One-pot synthesis of 3,4-dihydropyridin-2-ones via tandem reaction of Blaise reaction intermediate and acrylic ester.
- Source :
- Applied Organometallic Chemistry; Jan2016, Vol. 30 Issue 1, p47-50, 4p
- Publication Year :
- 2016
-
Abstract
- An efficient method for the synthesis 3,4-dihydropyridin-2-ones has been developed via tandem one-pot Michael-type addition and cyclization of the Blaise reaction intermediate and acrylic ester. A series of readily available nitriles, bromoacetic esters and acrylic esters have been employed to examine the scope of substrates for this method. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 02682605
- Volume :
- 30
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Applied Organometallic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 111991194
- Full Text :
- https://doi.org/10.1002/aoc.3399