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Induction of HLA-B*40:02-restricted T cells possessing cytotoxic and suppressive functions against haematopoietic progenitor cells from a patient with severe aplastic anaemia.
- Source :
- British Journal of Haematology; Jan2016, Vol. 172 Issue 1, p131-134, 4p
- Publication Year :
- 2016
-
Abstract
- The article offers information on a study concerning induction of human leucocyte antigen (HLA)-B restricted T cells possessing cytotoxic and suppressive functions against haematopoietic progenitor cells from a patient with severe aplastic anaemia. Topics discussed include treatment of acquired aplastic anaemia (AA) with antithymocyte globulin and ciclosporin (CsA), bone marrow (BM) hypoplasia and pancytopenia, and immune pressure of autoreactive cytotoxic T lymphocytes.
- Subjects :
- ANEMIA treatment
HUMAN leucocytes
ANTIGENS
IMMUNOGLOBULINS
T cells
PROGENITOR cells
Subjects
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 172
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 112011159
- Full Text :
- https://doi.org/10.1111/bjh.13464