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Gastrointestinal perforation after liver transplantation.
- Source :
- Surgical Practice; Feb2016, Vol. 20 Issue 1, p8-12, 5p, 1 Black and White Photograph, 3 Charts, 1 Graph
- Publication Year :
- 2016
-
Abstract
- Aim The aim of the present study was to evaluate the risk factors and outcomes of gastrointestinal perforation post-liver transplantation. Patients and Methods Eleven patients were found to have complications as a result of gastrointestinal perforation post-liver transplantation at our centre from May 2008 to February 2014. Seven of these patients were selected for statistical analysis. Each patient was randomly matched with six recipients in age (± 10 years), primary disease and sex. Factors, including cold ischaemic time, blood loss volume, previous hepatobiliary surgery history and 1-year survival rate, were compared between the two groups. Results The sites of perforation were the stomach ( n = 2), duodenum ( n = 2), jejunum ( n = 1), ileum ( n = 3) and colon ( n = 3). Univariate analysis showed a significant difference in previous hepatobiliary surgery history ( P < 0.01). No difference was found in portal venous cross-clamp time, cold ischaemic time, model for end-stage liver disease score, body mass index, steroid therapy or blood type incompatibility. Previous hepatobiliary surgery history was found to be an independent risk factor in the multivariate analysis ( P < 0.05). The 1-year survival rate was lower in the perforation group ( P < 0.01). Conclusion Gastrointestinal perforation leads to a high rate of morbidity and mortality, and significantly decreases graft and recipient survival. A history of hepatobiliary surgery is a risk factor of this complication. Careful dissection and avoiding iatrogenic injury during operation are important. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 17441625
- Volume :
- 20
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Surgical Practice
- Publication Type :
- Academic Journal
- Accession number :
- 112335054
- Full Text :
- https://doi.org/10.1111/1744-1633.12154