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Silver-catalyzed oxidative decarboxylation of difluoroacetates: efficient access to C–CF2 bond formation.
- Source :
- Chemical Communications; 1/28/2016, Vol. 52 Issue 8, p1598-1601, 4p
- Publication Year :
- 2016
-
Abstract
- A mild, versatile and efficient method for the silver(i)-catalyzed oxidative decarboxylative gem-difluoromethylenation has been developed. The radical cascade reaction comprises the addition of an oxidatively generated difluoromethylene radical to the isonitrile functionality and subsequent homolytic aromatic substitution. It provides a novel and efficient access to the C–CF<subscript>2</subscript> bond formation. [ABSTRACT FROM AUTHOR]
- Subjects :
- SILVER catalysts
DECARBOXYLATION
FLUOROACETATES
BOND formation mechanism
ISOCYANIDES
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 52
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 112408324
- Full Text :
- https://doi.org/10.1039/c5cc09179a