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Do zopiclone, zolpidem and flunitrazepam have residual effects on simulated task of collision anticipation?
- Source :
- Journal of Psychopharmacology; Sep2003, Vol. 17 Issue 3, p324-331, 8p
- Publication Year :
- 2003
-
Abstract
- Few studies have addressed the modifications in visual information processing brought about by taking hypnotic substances. The present experiment with healthy subjects investigated the residual effects of taking a single night-time dose of hypnotics on collision anticipation capacities the next morning. Visual sequences simulated the movement of a driver approaching an intersection where another vehicle was arriving. Ten participants had to estimate, as quickly as possible, whether the other vehicle would arrive before or after them at the intersection. They were tested after having taken a capsule of zolpidem (10 mg), zopiclone (7.5 mg), flunitrazepam (1 mg) or a placebo. The results show no residual effects of the molecules. Only flunitrazepam, a benzodiazepine with a long half-life, appears to cause subjects to focus their attention on an element which, while relevant for the task (a road sign playing the role of a spatial reference), is not used correctly. [ABSTRACT FROM AUTHOR]
- Subjects :
- HUMAN information processing
HYPNOTICS
ZOLPIDEM
CENTRAL nervous system depressants
AUTOMOBILE driving
TRAFFIC accidents -- Psychological aspects
ATTENTION
CLINICAL trials
COMPARATIVE studies
FLUNITRAZEPAM
HETEROCYCLIC compounds
RESEARCH methodology
MEDICAL cooperation
ORGANIC compounds
PYRIDINE
RESEARCH
TIME
TASK performance
EVALUATION research
PSYCHOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 02698811
- Volume :
- 17
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of Psychopharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 11296217
- Full Text :
- https://doi.org/10.1177/02698811030173015