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Study of Stereocontrolling Elements in Chiral Phosphoric Acid Catalyzed Addition Reaction of Vinylindoles with Azlactones.

Authors :
Kyohei Kanomata
Masahiro Terada
Source :
Synlett; 2016, Vol. 27 Issue 4, p581-585, 5p
Publication Year :
2016

Abstract

DFT studies were carried out to clarify the reaction mechanism and the stereocontrolling elements in the addition reaction of vinylindoles with azlactones catalyzed by a chiral phosphoric acid. The results suggest that the reaction proceeds via a six-membered transition state that is composed of the vinyl group of vinylindole and the enol moiety of azlactone. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09365214
Volume :
27
Issue :
4
Database :
Complementary Index
Journal :
Synlett
Publication Type :
Academic Journal
Accession number :
113146495
Full Text :
https://doi.org/10.1055/s-0035-1561677