Secondary and tertiary structure prediction of fenugreek (Trigonella foenum-graecum) protein.

In-silico development of protein models in fenugreek (Trigonella foenum-graecum) has opened up new vistas using the modern computational tools. The identification of protein in fenugreek having homology with the protein domain of humans and E-coli shows that the database available on Apiaceae family are very low. The estimated molecular weight of identified for fenugreek AM-1 protein was 11372.8 and was predicted as basic. A channel in fenugreek transmembrane protein has been identified through which a ligand (an ion or a small molecule) might pass. The present finding may be a valuable addition to the proteomic information available on fenugreek. Further validation can be performed using wet lab experiments. [ABSTRACT FROM AUTHOR]