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Prevention and Treatment of Anemia in Infants through Supplementation, Assessing the Effectiveness of Using Iron Once or Twice Weekly.
- Source :
- Journal of Tropical Pediatrics; Apr2016, Vol. 62 Issue 2, p123-130, 8p
- Publication Year :
- 2016
-
Abstract
- <bold>Background: </bold>The objective of this study was to compare the effect of once weekly iron supplementation (IS) versus twice weekly, on hemoglobin (Hb) levels and anemia prevalence.<bold>Methods: </bold>In this cluster-randomized clinical trial study, we evaluated infants aged 6-18 months. Length of intervention: 16 weeks. Infants were cluster randomized to either 25 mg elemental iron once weekly (Group-A) or twice weekly (Group-B). Primary outcome variables were change in Hb concentration and anemia prevalence. Two biochemical evaluations were performed to determine Hb concentrations, before and after intervention.<bold>Results: </bold>For Group-A, at baseline, mean Hb concentration was 10.8 ± 1.18 g/dl and after intervention 11.2 ± 1.07 g/dl,p = 0.12; anemia prevalence was 52.5% at baseline and 37.5% after intervention,p = 0.18; Group-B, mean baseline Hb was 10.7 ± 1.04 g/dl, and 11.3 ± 0.91 g/dl after intervention,p = 0.002; anemia prevalence reduced from 57.9 to 36.8%.<bold>Conclusions: </bold>Both once and twice weekly IS increased mean Hb concentration; however, twice weekly supplementation provided more significant results. [ABSTRACT FROM AUTHOR]
- Subjects :
- IRON deficiency diseases in infants
IRON deficiency anemia treatment
DIETARY supplements
INFANT health
INFANT nutrition
DISEASE prevalence
IRON deficiency anemia prevention
CLUSTER analysis (Statistics)
COMPARATIVE studies
DRUG administration
DOSE-effect relationship in pharmacology
FERRITIN
HEMOGLOBINS
IRON compounds
IRON deficiency anemia
RESEARCH methodology
MEDICAL cooperation
RESEARCH
TIME
SOCIOECONOMIC factors
EVALUATION research
RANDOMIZED controlled trials
TREATMENT effectiveness
Subjects
Details
- Language :
- English
- ISSN :
- 01426338
- Volume :
- 62
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Journal of Tropical Pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 114160318
- Full Text :
- https://doi.org/10.1093/tropej/fmv085