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Computed tomography and magnetic resonance features of intracranial hemangioendothelioma: A study of 7 cases.

Authors :
WEI-ZHONG TIAN
XIANG-RONG YU
WEI-WEI WANG
BO ZHANG
JIAN-GUO XIA
HAN-QIU LIU
Source :
Oncology Letters; May2016, Vol. 11 Issue 5, p3105-3110, 6p
Publication Year :
2016

Abstract

The current study aimed to present the neuro-radiological and histopathological features of intracranial hemangioendothelioma (HE). The computed tomography (CT; n=3) and magnetic resonance imaging (MRI; n=7) features, and the clinical presentations of 7 patients with pathologically documented HEs were retrospectively analyzed. Lesions were observed in the right side of the skull (the frontal bone in 1 patient and the parietal bone in 1 patient), the tentorium (2 patients), the cerebral falx (1 patient), the right cavernous sinus (1 patient) and the right temporal lobe (1 patient). The tumor was lobulated in 5 cases and round in 2 cases. The majority of tumors appeared isointense or hypointense with multiple scattered hyperintensities on T1-weighted MRI. Moreover, the lesions appeared as inhomogeneous hyperintense regions with multiple enlarged and tortuous blood flow voids on T2-weighted MRI. The lesions also showed marked gadolinium enhancement in a honeycomb pattern. CT scan results showed a isoattenuation region (32-47 HU), with numerous small, round, high-density foci. The 2 cases with skull lesions presented with local bone destruction and discontinuous bone lines of the tabula interna ossis cranii. In 1 case, MR angiography revealed abnormal vessels in the basilar region. A total of 4 cases were epithelial HE, 2 were retiform HE and 1 was kaposiform HE. Histological examination revealed endothelial cell proliferation with vascular lesions and a mucous matrix or dense fibrous mesenchyme. In conclusion, intracranial HE is rare, but should be considered in the differential diagnosis when evaluating intracranial neoplasms. A well-defined lobulated mass and imaging features that include internal heterogeneity, small scattered hemorrhages and thromboses, signal voids of vessels, and marked and delayed enhancement may confirm the diagnosis of HE. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17921074
Volume :
11
Issue :
5
Database :
Complementary Index
Journal :
Oncology Letters
Publication Type :
Academic Journal
Accession number :
114528012
Full Text :
https://doi.org/10.3892/ol.2016.4356