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Effects of ventricular conduction block patterns on mortality in hospitalized patients with dilated cardiomyopathy: a single-center cohort study.
- Source :
- BMC Cardiovascular Disorders; 6/13/2016, Vol. 16, p1-8, 8p, 1 Color Photograph, 1 Diagram, 2 Charts, 1 Graph
- Publication Year :
- 2016
-
Abstract
- <bold>Background: </bold>Ventricular conduction blocks (VCBs) are associated with poor outcomes in patients with known cardiac diseases. However, the prognostic implications of VCB patterns in dilated cardiomyopathy (DCM) patients need to be evaluated. The purpose of this study was to determine all-cause mortality in patients with DCM and VCB.<bold>Methods: </bold>This cohort study included 1119 DCM patients with a median follow-up of 34.3 (19.5-60.8) months, patients were then divided into left bundle branch block (LBBB), right bundle branch block (RBBB), intraventricular conduction delays (IVCD) and narrow QRS groups. The all-cause mortality was assessed using Kaplan-Meier survival curves and Cox regression.<bold>Results: </bold>Of those 1119 patients, the all-cause mortality rates were highest in patients with IVCD (47.8, n = 32), intermediate in those with RBBB (32.9, n = 27) and LBBB (27.1 %, n = 60), and lowest in those with narrow QRS (19.9 %, n = 149). The all-cause mortality risk was significantly different between the VCB and narrow QRS group (log-rank χ2 = 51.564, P < 0.001). The presence of RBBB, IVCD, PASP ≥ 40 mmHg, left atrium diameter and NYHA functional class were independent predictors of all-cause mortality in DCM patients.<bold>Conclusions: </bold>Our findings indicate that RBBB and IVCD at admission,but not LBBB, were independent predictors of all-cause mortality in patients with DCM. [ABSTRACT FROM AUTHOR]
- Subjects :
- HEART ventricles
HEART conduction system
HEART disease related mortality
CARDIAC patients
CARDIOMYOPATHIES
COHORT analysis
ACTION potentials
CHI-squared test
COMPARATIVE studies
CAUSES of death
DOPPLER echocardiography
ELECTROCARDIOGRAPHY
HEART beat
HEART block
HOSPITAL care
RESEARCH methodology
MEDICAL cooperation
MULTIVARIATE analysis
PROGNOSIS
RESEARCH
RISK assessment
TIME
EVALUATION research
PREDICTIVE tests
PROPORTIONAL hazards models
RETROSPECTIVE studies
DILATED cardiomyopathy
KAPLAN-Meier estimator
DIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 14712261
- Volume :
- 16
- Database :
- Complementary Index
- Journal :
- BMC Cardiovascular Disorders
- Publication Type :
- Academic Journal
- Accession number :
- 116151903
- Full Text :
- https://doi.org/10.1186/s12872-016-0313-4