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Implementing a screening program for acromegaly in Latin America: necessity versus feasibility.

Authors :
Danilowicz, Karina
Day, Patricia
Manavela, Marcos
Herrera, Carlos
Deheza, María
Isaac, Gabriel
Juri, Ariel
Katz, Debora
Bruno, Oscar
Source :
Pituitary; Aug2016, Vol. 19 Issue 4, p370-374, 5p
Publication Year :
2016

Abstract

Introduction: Acromegaly is a rare disease with a large burden due its associated comorbidities and the life-long management required. Since the occurrence and severity of associated complications are related to length of exposure to the excess growth hormone seen in acromegaly, early diagnosis is imperative. The delay in diagnosis, however, can be long, and may be the result of a lack of disease awareness and screening programs. Since acromegaly is an uncommon disease, finding ways to increase recognition and diagnosis that would permit early detection in a logical and cost-effective manner could be a challenge. Methods: We conducted a retrospective literature review for information relating to the screening and diagnosis of acromegaly using PubMed. The aim was to assess whether an acromegaly-screening program in Latin America (and elsewhere) would be both of use and be feasible. Findings and conclusions: An earlier diagnosis allows earlier initiation of treatment, such as surgery and/or drugs, which leads to more successful disease management (biochemical control) and better outcomes. Since the delay in diagnosis can be long, we believe that clear opportunities exist for earlier (and increased) detection of acromegaly. This can be achieved by increasing disease awareness for earlier recognition of symptoms and by using targeted screening (rather than mass screening) programs. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1386341X
Volume :
19
Issue :
4
Database :
Complementary Index
Journal :
Pituitary
Publication Type :
Academic Journal
Accession number :
116645481
Full Text :
https://doi.org/10.1007/s11102-016-0714-5