Pancreatitis associated with metformin used for management of clozapine-related weight gain.

The article presents a case study of a 17-year-old male with treatment resistant schizophrenia and moderate intellectual disability treated with clozapine and metformin, who was presented with intermittent nausea and vomiting. It mentions that the patient was diagnosed with intermittent pancreatitis secondary to high-dose metformin. It states that the pathogenesis of metformin-induced pancreatitis is not known.