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The pathogenesis of mycosis fungoides.
- Source :
- Clinical & Experimental Dermatology; Mar1981, Vol. 6 Issue 1, p77-87, 11p
- Publication Year :
- 1981
-
Abstract
- The article focuses on the pathogenesis of mycosis fungoides (MF). MF is a cutaneous lymphoma characterized by an initially polymorphous infiltrate composed largely of T-lymphocytes. The dermal infiltrate invades the epidermis, forming small accumulations of T-lymphocytes termed Pautrier's microabscesses. Atypical lymphocytes with hyperconvoluted nuclei, termed as Lutzner or mycosis cells, are found in the cutaneous infiltrates, lymph nodes, or peripheral blood of MF patients. A leukaemic variant of MF, the Sézary syndrome, is characterized by erythroderma and a large percentage of a typical lymphocytes in the peripheral blood and tissue infiltrates.
- Subjects :
- MYCOSIS fungoides
LYMPHOMAS
T cells
EPIDERMIS
MYCOSES
CELLS
LYMPH nodes
LYMPHOCYTES
Subjects
Details
- Language :
- English
- ISSN :
- 03076938
- Volume :
- 6
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Clinical & Experimental Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 11691285
- Full Text :
- https://doi.org/10.1111/j.1365-2230.1981.tb02270.x