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Primary rhabdomyosarcoma of the distal femoral diaphysis: a case report and review of the literature.

Authors :
Bressner, Jarred
McCarthy, Edward
Fayad, Laura
Morris, Carol
Bressner, Jarred A
McCarthy, Edward F
Fayad, Laura M
Morris, Carol D
Source :
Skeletal Radiology; Oct2016, Vol. 45 Issue 10, p1391-1395, 5p
Publication Year :
2016

Abstract

Primary rhabdomyosarcoma of the bone is an extremely rare condition with few examples reported in the literature. We present the case of a 34-year-old male who presented with a lesion in the distal femur with initial imaging features consistent with Ewing sarcoma. Histologically, the lesion consisted of atypical pleomorphic polygonal rhabdomyoblasts demonstrating focal desmin and myogenin expression. A diagnosis of pleomorphic rhabdomyosarcoma was rendered. Despite systemic treatment and surgery, this patient experienced a rapidly progressive disease course. We believe this is only the second report in the orthopedic literature of a case of primary pleomorphic rhabdomyosarcoma of the bone. The key imaging, pathologic, and clinical findings are discussed. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03642348
Volume :
45
Issue :
10
Database :
Complementary Index
Journal :
Skeletal Radiology
Publication Type :
Academic Journal
Accession number :
117879218
Full Text :
https://doi.org/10.1007/s00256-016-2430-7